There are 15 activities in total split up in to five different categories: Visualize, Memorize, Analyze, Compute and Identify.
Activities range from popping marked balloons in the proper order, to identifying the "odd-one-out" from a series of pictures.
When you first start the game you take a testing quiz that determines your base "brain size" and how strong you are in each of the five categories. Upon subsequent gaming sessions the game calculates your new scores and how you've improved. The game even suggests various jobs that you might be suitable for.
The Wii version of the game introduces a multiplayer mode that allows for up to eight players to compete against one another. Two players go head to head in completing a sequence of mini-games with the person achieving the higher score winning. Eight players can compete by splitting up into teams and the overall score of the team determining the winner.